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M.Sc. Josefa Hofmann

Department Chemie und Pharmazie
Lehrstuhl für Pharmazeutische Chemie
Schuhstr. 19
91052 Erlangen

Tel.: (+49)-(0)9131-85-23921
Room: 0.033-0.036

josefa.hofmann@fau.de

Research Topics

  • Gomberg-Bachmann chemistry and reactions
  • applications in medicinal chemistry

Curriculum Vitae

  • since 2014 Ph.D. in Organic / Pharmaceutical Chemistry with Prof. Dr. Markus Heinrich, Friedrich-Alexander-Universität Erlangen-Nürnberg: "Entwicklung radikalischer und nicht-radikalischer Arylierungsreaktionen mit Anwendungen in der pharmazeutischen Chemie"
  • 2012-2014 Studies for Molecular Science (Master of Science) at the Friedrich-Alexander-Universität Erlangen-Nürnberg; Master thesis in the workgroup of Prof. Dr. Markus Heinrich (Pharmazeutische Chemie, Friedrich-Alexander-Universität Erlangen-Nürnberg): "Synthesis of 2-aminobiphenyls and application in medicinal chemistry" 
  • 2011/2012 Internship in the field of biochemistry in the Research&Development Department at Genor BioPharma Co. Ltd., Shanghai, P.R. China
  • 2008-2011 Studies for Molecular Science (Bachelor of Science) at the Friedrich-Alexander-Universität Erlangen-Nürnberg; Bachelor thesis in the workgroup of Prof. Dr. Nicolai Burzlaff (Anorganische Chemie, Friedrich-Alexander-Universität Erlangen-Nürnberg): "Modell-Komplexe für Peptid-Deformylasen"  
  • 1999-2008 Christoph-Jacob-Treu Gymnasium, Lauf a. d. Pegnitz 
  • 1995-1999 Primary school, Schnaittach
  • 1989 born in Fürth

Publications

Strongly directing substituents in the radical arylation of substituted benzenes
J. Hofmann, T. Clark, M. R. Heinrich, J. Org. Chem. 2016, 81, 9785-9791
DOI: 10.1021/acs.joc.6b01840
Recent developments in intramolecular radical arylations of arenes and heteroarenes
J. Hofmann, M. R. Heinrich, Tetrahedron Lett. 2016, 57, 4334-4340 (short review)
DOI: 10.1016/j.tetlet.2016.08.034
Denitrification combined with diazotization of anilines and the synthesis of 4’ chlorobiphenyl-2,5-diamine and 1-chloro-4-iodobenzene
D. Hofmann, J. Hofmann, L. Hofmann, L.-E. Hofmann, M. R. Heinrich, Org. Process Res. Dev. 2015, 19, 2075-2084.
DOI: 10.1021/acs.oprd.5b00298
Oxidative radical arylation of anilines with arylhydrazines and dioxygen from air
J. Hofmann, H. Jasch, M. R. Heinrich, J. Org. Chem. 201479, 2314–2320
DOI: 10.1021/jo500063r