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Dr. Sarah Haug (geb. Höfling)


Ph.D. Thesis


Curriculum Vitae

  • 2008-2011 Ph.D. in Organic / Pharmaceutical Chemistry with Prof. Dr. Markus Heinrich, Technische Universität München / Friedrich-Alexander-Universität Erlangen-Nürnberg
  • 2006-2008 Studies for Chemistry (Master of Science) at the Technische Universität München; Master thesis in the workgroup of Prof. Dr. Thorsten Bach (Organische Chemie I, Technische Universität München): "Development of new methods in radical chemistry for the synthesis of [18]fluorinelabelled radiodiagnostics" 
  • 2003-2006 Studies for Chemistry (Bachelor of Science) at the Technische Universität München; Bachelor thesis in the workgroup of Prof. Dr. Thorsten Bach (Organische Chemie I, Technische Universität München): "Synthesis of 3,4-dihydro-5-phenyl-2-pyridones for their use in enantioselective [2+2]-photocycloadditions"   
  • 1994-2003 Ignaz-Taschner-Gymnasium, Dachau 
  • 1990-1994 Primary school, Munich-Karlsfeld
  • 1984 born in Dachau

Publications

Fast and efficient 18F-labeling via [18F]fluorophenylazocarboxylic esters
S. Fehler, S. Maschauer, S. Höfling, A. Bartuschat, N. Tschammmer, H. Hübner, P. Gmeiner, O. Prante, M. R. Heinrich, Chem. Eur. J.  2014, 20, 370-375
DOI: 10.1002/chem.201303409
Method for synthesising aminobiphenyls using aryl hydrazines
M. Heinrich, H. Jasch, S. Höfling, WO2013132006
Nucleophilic substitutions and radical reactions of phenylazocarboxylates
H. Jasch, S. B. Höfling, M. R. Heinrich, J. Org. Chem. 2012, 77, 1520-1532
DOI: 10.1021/jo202406k
Nitrogen-centered radical scavengers
S. B. Höfling, M. R. Heinrich, Synthesis (Review) 2011, 173-189
DOI: 10.1055/s-0030-1258305
Synthesis, biological evaluation and radiolabeling by 18F-fluoroarylation of a dopamine D3 selective ligand as prospective imaging probe for PET
S. B. Höfling, S. Maschauer, H. Hübner, P. Gmeiner, H.-J. Wester, O. Prante, M. R. Heinrich, Bioorg. Med. Chem. Lett. 2010, 20, 6933-6937
DOI: 10.1016/j.bmcl.2010.09.142
4-Substituted tert-butyl phenylazocarboxylates - synthetic equivalents for the para-phenyl radical cation
S. B. Höfling, A. L. Bartuschat, M. R. Heinrich, Angew. Chem. 2010, 122, 9963-9966, Angew. Chem. Int. Ed. 201049, 9769-9772
DOI: 10.1002/ange.201004508; DOI: 10.1002/anie.201004508
Radiochemical [18F]fluoroarylation of unsaturated α-, β- and γ-amino acids, application to a radiolabeled derivate of baclofen
S. B. Höfling, C. Hultsch, H.-J. Wester, M. R. Heinrich, Tetrahedron 2008, 64, 11846-11851
DOI: 10.1016/j.tet.2008.07.117